Ruedi Kuenzli taught courses at the University of Iowa in contemporary theories, literatures and cultures of the 19th and 20th centuries, interarts, and the avant-garde.

He has published books on Marcel Duchamp, Dada and Surrealist Film, André Breton, Surrealism and Women, and New York Dada. He served as the editor of Dada/Surrealism and the Director of the International Dada Archive at the University of Iowa.